This study was carried out to assess the incidence of breast cancer among females in Ethiope East and Ethiope West L.G.A.s of Delta State. Five research questions were raised and answered. A descriptive survey research design was adopted for the study. The population of the study consists of 265,349 females from Ethiope East and Ethiope West Local Government Areas of Delta State. The sample size of the study was 400 respondents. Data for this study was collected using a questionnaire. A reliability coefficient value of 0.75 was obtained for the questionnaire.